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Lyme Disease Vaccine (Recombinant OspA) What is LYMErix? LYMErix is a new genetically engineered vaccine that prevents Lyme disease by killing the bacterium that causes infection. LYMErix contains a protein called ospA adsorbed onto aluminum hydroxide. How does LYMErix work? After your first does of LYMErix, your body’s immune system should begin to produce the antibodies needed to attach the germ that causes Lyme disease, Borrelia Burgdorferi (bo-re’-le-a berg-dor’-fer-I). When a tick bites you and draws a blood meal, it ingests these antibodies present in the blood. If that tick is infected with the organism that causes Lyme disease, your antibodies will kill those Borrelia burgdorferi germs inside of the tick and prevent them from ever entering your body. Do I need to be vaccinated with LYMErix more than once?For optimal protection, you need to receive 3 LYMErix vaccinations over a 1-year period. After your first dose, you should have your second dose 1 month later and your third dose 11 months after that. Is there a chance I might get Lyme disease from LYMErix? No. There is no risk of getting Lyme disease from LYMErix since it cannot cause infection. Can everyone in my family get vaccinated with LYMErix? LYMErix has been proven safe and effective for people 15 through 70 years of age. Safety and efficacy in pediatric subjects younger than 15 years of age have not been evaluated. LYMErix is not indicated for any other age group at this time. There is, however, a large-scale, clinical study currently under way to determine the safety and effectiveness of LYMErix in children as young as 4 years of age. How can I be confident LYMErix
will protect me? If I’ve already had Lyme disease, do I still need to get vaccinated with LYMErix? Yes. Even if you have been successfully treated for Lyme disease, you are still at risk. Unlike other diseases you may be aware of, people don’t develop resistance to Lyme disease after infection. In fact, if you contracted Lyme disease once, you may continue to be at high risk for getting Lyme disease because you most likely live, work or recreate in areas where Lyme disease is present. Can LYMErix treat a current
Lyme disease infection? Will LYMErix affect my
future laboratory test for Lyme disease? After
vaccination with LYMErix, you should be aware that LYMErix may cause a
false-positive result if your blood is tested for Lyme disease by an ELISA blood
test. Does LYMErix have any
side effects? Are there any individuals who
should not receive LYMErix? What happens if I don’t get
all 3 LYMErix vaccinations? As a participant in this special program, you will automatically receive friendly reminders before each dose is due. To enroll, talk with your doctor. In addition to vaccination
with LYMErix are there any other steps I can take to prevent Lyme disease? Call toll free: 1-888-LYMErix, extension 300, or visit their Website @www.lymerix.com for more information about Lyme disease and LYMErix. |